A new study explores the relationship between frailty, the proportion of health deficits present in an individual, as measured by the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI), and future health-related quality of life (HRQoL) in people with systemic lupus erythematosus (SLE).
The study, conducted with a Latin American Mestizo SLE cohort from the Grupo Latino Americano de Estudio del Lupus (GLADEL) registry, tracked 428 people with SLE over 2,645 visits for an average of 4.71 years. Researchers evaluated whether SLICC-FI scores from one visit could predict subsequent HRQoL scores at the next visit. Models were adjusted for various factors like age, sex, socioeconomic status, disease activity, and medication use. Researchers found that a higher SLICC-FI score could predict lower quality of life, especially in the categories of pain, planning, emotional health, and fatigue.
The study suggests that the SLICC-FI is an effective tool for identifying people with lupus at higher risk of poor quality of life and highlights the importance of comprehensive assessments that go beyond traditional disease activity and organ damage measures to improve care for people with lupus.
Learn more about health-related quality of life research for those with lupus here.
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