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RINVOQ Continues to Show Promise for Lupus Treatment

by | May 31, 2023

Inside Lupus Research (ILR): Treatment News

AbbVie announced today that its drug therapy upadacitinib (also known as RINVOQ®) met its primary and secondary endpoints when administered alone or as a combination therapy for treatment of moderate to severe active lupus in individuals receiving standard disease therapies. The drug is advancing to Phase 3 clinical trial for treatment of lupus. RINVOQ is already approved for the treatment of other autoimmune conditions, such as rheumatoid arthritis, psoriatic arthritis, and eczema.

In the SLEek Phase 2 trial of RINVOQ, the drug was given alone to trial participants in a 30-mg dose or as a combination therapy with elsubrutinib (60-mg dose) at week 24. At week 48, both groups exhibited improved active disease.

Continue to follow the Lupus Foundation of America for updates on RINVOQ as well as other lupus clinical trials.

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