A study found that ginger supplements may help control inflammation in certain autoimmune diseases, including lupus and rheumatoid arthritis. Researchers found that daily consumption of a ginger supplement can make neutrophil cells more resistant to neutrophil extracellular trap (NET) formation or NETosis, a unique form of cell death, in healthy people and autoimmune mice. NETs are elevated in the plasma of people with autoimmune diseases. Inside the body, NETs are composed of DNA and have a central role in immune defense, protecting against infection and supporting immune-modulatory functions.
The researchers explored ginger consumption benefits in mice with antiphospholipid syndrome or lupus. Mice were given a ginger extract by mouth which resulted in reduced NETs and disease activity. The scientists then tested healthy people. Human participants were given a ginger supplement of 100 mg once daily for 7 days and were monitored for 7 additional days after their last dose. Their blood was sampled prior to starting the supplement and then again on day 7 and day 14. Analysis revealed the neutrophils in healthy people became more resistant to NETosis. The same studies were conducted at a second site with similar results.
More research is needed to understand the impact of ginger supplementation on the neutrophils of people with inflammatory diseases, like lupus. Talk to your doctor to discuss whether ginger supplements could be a beneficial part of your treatment plan. Follow the Lupus Foundation of America for updates on the latest lupus research.
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